Assessment of Pain and Antibacterial Activity of Chitosan Versus Sodium Hypochlorite as Irrigant in Infected Canal

• Status: Unknown status
• Trial end date: 2019-10-01
• Target enrollment: 0
• Participant gender: All

Summary

A randomized clinical trial that aims to study the effect of chitosan nanoparticles (CS-np) versus sodium hypochlorite as a root canal irrigant on postoperative pain and antibacterial activity against E.faecalis in infected root canal.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cairo University
• Treatments: Anti-Bacterial Agents; Chitosan; Eusol; Sodium Hypochlorite

Criteria

Inclusion Criteria:

• Young adult Patients, both genders, aging from 18-45 years.

• Patients with permanent mature teeth (closed apex).

• Single rooted single canal necrotic anterior teeth without apical periodontitis or with slight widening of peridontium.

• Patients should be free from any systemic disease.

• Patients with normal periodontal depth less or equal 3 mm.

• Patients who will agree to the consent and will commit to follow-up.

Exclusion Criteria:

• Patients with permanent immature teeth.

• Teeth with vital pulps.

• Patients with facial swelling or acute infection or pain on percussion

• Patients with fistula.

• Teeth with vertical root fractures, internal or external root resorption and calcification

• Teeth with periodontal involvement or periapical bone loss.

• Patients with any systemic disease that may affect predictable outcome.

• Pregnant or lactating females.

• Non-restorable teeth.