Assessing the Effectiveness of Midazolam Premedication

• Status: Completed
• Trial end date: 2017-08-15
• Target enrollment: 0
• Participant gender: Female

Summary

Pre-anesthetic dosing of midazolam is commonly used in many hospitals for the induction of anesthesia, but the effect is still controversial. The purpose of this study was to evaluate the effectiveness of midazolam premedication in four aspects: anxiety reduction, pain relief, sedation and hemodynamic stability.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pusan National University Hospital
• Treatments: Midazolam; Propofol; Remifentanil

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists physical status classification I or II

• Scheduled for elective thyroidectomy under general anesthesia

Exclusion Criteria:

• Central nervous system disorders

• Major cardiovascular disease

• Chronic pain disorders

• Peripheral neuropathy

• Diabetes mellitus neuropathy

• Nephropathy

• Hepatopathy

• Taking any medication affecting the central nervous system or heart rate

• Alcohol or drug abuse

• Pregnancy

• Contraindication to midazolam premedication