Overview

Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies

Status:
Recruiting

Trial end date:
2024-08-01

Target enrollment:
0

Participant gender:
All

Summary

This is a randomized study that will enroll patients scheduled for an endoscopic biopsy of a pancreas lesion to be in the heparin or saline group during the procedure. The purpose of this study is to examine the effect of blood contamination, heparin priming of the fine needle biopsies, and pass number on tumor tissue quality in fine needle biopsies. The hypothesis for this study is that fine needle biopsy tissue quality of pancreatic masses decreases with increasing pass number due to blood contamination; this blood contamination can be ameliorated with priming of the needle with an anticoagulant such as heparin.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of Michigan

Treatments:

Calcium heparin
Heparin

Criteria

Inclusion Criteria:

- patients identified as having a possible solid lesion in their pancreas on
radiographic imaging

- scheduled for endoscopic fine needle biopsy (FNB) for clinical purposes.

Exclusion Criteria:

- known history of coagulopathy

- history of heparin allergy

- patients with evidence of vascular tumors on imaging