Overview

Assess the Safety, Tolerability Oral PU-H71 in Subjects Taking Ruxolitinib

Status:
Recruiting
Trial end date:
2022-05-30
Target enrollment:
Participant gender:
Summary
This is a multicenter, Phase 1b study with dose escalation and expansion cohorts designed to assess the safety, tolerability, PK, and preliminary efficacy of PU-H71 in subjects with PMF, Post-PV MF, Post-ET MF, taking stable doses of ruxolitinib.
Phase:
Phase 1
Details
Lead Sponsor:
Samus Therapeutics, Inc.
Treatments:
9H-purine-9-propanamine, 6-amino-8-((6-iodo-1,3-benzodioxol-5-yl)thio)-N-(1-methylethyl)-