Overview

Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects

Status:
Completed
Trial end date:
2019-11-04
Target enrollment:
Participant gender:
Summary
Study to determine the effect of multiple-dose BBT-877 on the single-dose pharmacokinetics of midazolam, the safety and tolerability of a single dose of BBT-877 administered alone and with multiple doses of itraconazole, and the effect of multiple-dose esomeprazole on the single-dose pharmacokinetics of BBT-877, in healthy adult subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Bridge Biotherapeutics, Inc.
Collaborator:
KCRN Research, LLC
Treatments:
Esomeprazole
Hydroxyitraconazole
Itraconazole
Midazolam