Assess Particle Deposition and Acute Effects of Symbicort® Forte Turbohaler®) in COPD Patients.
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
Computational Fluid Dynamics (CFD) is a new functional imaging method. Since CFD is very
sensitive to detect small changes, it might be worthwhile to study the acute effect of
formoterol and budesonide combination therapy (Symbicort® forte Turbohaler®) on the upper
airway dimensions in severe COPD patients (GOLD III). The increased sensitivity of this
technique makes it possible to detect changes in airway caliber in early stages. The regional
distribution of resistance and the change in this parameter will provide more insight into
the mode of action of the product.
Phase:
Phase 4
Details
Lead Sponsor:
University Hospital, Antwerp
Collaborator:
AstraZeneca
Treatments:
Budesonide Budesonide, Formoterol Fumarate Drug Combination Formoterol Fumarate