Aspirin for Exercise in Multiple Sclerosis (ASPIRE)
Status:
Recruiting
Trial end date:
2022-01-01
Target enrollment:
Participant gender:
Summary
This study investigates the use of aspirin as an exercise pre-treatment to reduce overheating
and exhaustion, which may potentially allow many more people with multiple sclerosis to
participate in and benefit from exercise. The design is double-blind, within-subject, with
three arms: participants will receive one of three treatments at three separate study visits:
aspirin, acetaminophen, and placebo, followed by completion of a maximal exercise test.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Columbia University
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health (NIH)