Charcot-Marie-Tooth type IA (CMT1A) is the most prevalent hereditary peripheral neuropathy.
Demyelination of peripheral nerves is the hallmark of CMT1A. Ascorbic acid has been shown to
have a favorable influence on myelination in in vitro studies and in a mouse model for CMT1A.
We will study the efficacy and safety of ascorbic acid treatment in young patients with
CMT1A.
Phase:
Phase 2
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)