Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels
Status:
Completed
Trial end date:
2010-05-01
Target enrollment:
Participant gender:
Summary
This study is designed to assess the pharmacokinetics and safety of an infusion of a single
dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the
Intensive Care Unit with documented low levels of natural gelsolin. It is believed that this
drug will raise the gelsolin levels in these patients and decrease the probability that they
will develop complications from their underlying disease such as organ system failure or
death.