Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer
Status:
Completed
Trial end date:
2005-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing,
or coming back. Estrogen can cause the growth of breast cancer cells. Hormone therapy using
arzoxifene or tamoxifen may prevent breast cancer by lowering the amount of estrogen the body
makes. The use of arzoxifene or tamoxifen may keep breast cancer from forming in women at
high risk for breast cancer.
PURPOSE: This randomized phase II trial is studying arzoxifene to see how well it works
compared to tamoxifen or a placebo in preventing breast cancer in premenopausal women at high
risk for breast cancer.