Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as arsenic trioxide and dexamethasone, work in
different ways to stop the growth of cancer cells, either by killing the cells or by stopping
them from dividing. Thalidomide may stop the growth of multiple myeloma by blocking blood
flow to the cancer. Giving arsenic trioxide together with ascorbic acid, dexamethasone, and
thalidomide may kill more cancer cells.
PURPOSE: This phase II trial is studying how well giving arsenic trioxide together with
ascorbic acid, dexamethasone, and thalidomide work in treating patients with multiple
myeloma.