Application of Photodynamic Therapy and Diode Laser for Endodontic Therapy of Young Permanent Teeth
Status:
Completed
Trial end date:
2018-05-15
Target enrollment:
Participant gender:
Summary
The pulp necrosis of permanent immature teeth implies the interruption of the root formation
and apical closure. Diode lasers have been used in many areas of dentistry, with tendency of
good results in canal and dentine disinfection. The bactericidal effect of high-power lasers
is based on dose dependent heat generation. Its antimicrobial effectiveness against diverse
microorganisms has already been demonstrated. Photodynamic therapy (PDT) is a two-step
therapeutic approach starting with the application of a photosensitizing agent and followed
by irradiation with light energy that is spectrally matched to activate the drug. The balance
between disinfection and the creation of an intracanal microenvironment conducive for the
proliferation of stem cells requires further investigation. Aims of study are to compare the
time required to obtain the clinical healing and the disappearance of clinical symptoms, and
absence of periapical radiolucency, by using PDT and diode laser, with standard disinfection
alone; to assess specificity of microbial load in permanent immature teeth, and root canal
disinfection ability of PDT and diode laser, in compare with standard disinfection alone.
Phase:
Phase 2
Details
Lead Sponsor:
Association of Paediatric and Preventive Dentists of Serbia