Application of Daptomycin in MRSA Infected Diabetic Foot in Comparison to Vancomycin Treatment
Status:
Terminated
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Objective of the study is to test whether Daptomycin (6 mg/kg bodyweight) is non-inferior in
treatment of severe diabetic foot infections (MRSA) in comparison to antibiotic treatment
with Vancomycin (effective blood-plasma concentration of 15 mg/l). In case of
microbiologically confirmed gram-negative co-infection effective antibiotic treatment
according to microbiologic analysis will be administered upon medical decision in both
therapy groups. The study will be carried out as a randomized, open label study.