The study aims at optimizing the long-term and extended management of patients with a first
episode of venous thromboembolism (proximal deep vein thrombosis with or without pulmonary
embolism) (VTE). Patients at high risk of recurrence (with altered D-dimer test), who had
received anticoagulation (whatever the drug used) for 12-15 months after the first episode of
thrombosis, will be treated with Apixaban 2,5 mg x 2 for 18 months as extended treatment.
Patients at low risk, with normal D-dimer test, will stop anticoagulation definitely.