Overview

Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa flavoring, and, dextromethorphan syrup, compared with placebo.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Montefiore Medical Center
Treatments:
Antitussive Agents
Capsaicin
Chlorpheniramine, phenylpropanolamine drug combination
Dextromethorphan
Diphenhydramine
Guaifenesin
Oxymetazoline
Phenylephrine
Phenylpropanolamine
Promethazine
Criteria
Inclusion Criteria:

- healthy adult nonsmokers

- onset of acute, viral upper respiratory tract infection (common cold) within 72 hours
of enrollment

Exclusion Criteria:

- smokers

- history of asthma or other respiratory disorders