Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe
Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
Among patients with stable coronary artery disease (CAD), it is not clear if the pleiotropic
effects of cholesterol reduction differ between high-dose simvastatin alone and combined
ezetimibe/simvastatin.
The investigators sought to compare the anti-inflammatory and anti-platelet effects of
ezetimibe 10 mg / simvastatin 20 mg (E10/S20) to simvastatin 80 mg (S80).