The proposed study will add to the growing understanding of platelet activity and platelet
inhibition in subjects with HIV. It will examine the relationship between platelet activity
and its inhibition by antiplatelet therapy (aspirin monotherapy and clopidogrel monotherapy)
in this high-risk cohort. Furthermore, it will provide important data on the mechanism of
platelet activity and its inhibition using biomarkers of platelet activity, inflammation,
immune activity and endothelial function and genetic expression profiling.
Phase:
Phase 2
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health