Silent brain infarction (SBI) or incidental infarct is common. Recent studies revealed
individuals with SBI have an increased risk of future stroke. Even though the 2014 AHA/ASA
recommendation for ischemic stroke and transient ischemic attack considered SBI as an entry
point for secondary prevention, convincing evidence with regard to the preventive efficacy of
antiplatelet therapy against incident stroke in SBI is scant. Investigators examine if
antiplatelet therapy can effectively decrease the incidence of future stroke in SBI
individuals.