Antiplaque Effect of Essential Oils With and Without Alcochol on an in Situ Model of Oral Biofilm Growth
Status:
Unknown status
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
The accumulation and maturation of oral biofilm in the gingival margin is widely recognised
to be the primary aetiological factor in the development of chronic gingivitis. Based on this
association, the current treatment of gingivitis is focused on biofilm disruption, which will
normally include mechanical processes, both professionally and at home. However, for
patients, it is not easy to achieve a proper level of plaque control. The efficient plaque
control techniques are very time consuming and require a special motivation and skills for
their optimum use. It was at this point where mouthwashes become important, due to the fact
that they include diverse types of antimicrobial agents to complement the results of
mechanical oral hygiene measures.
The essential oils have been presented as a realiable alternative to the "gold Standard"
(Chlorhexidine). However, it use has been limited clinically due to their alcohol contain.
Some years ago, a new alternative without alcohol has been launched to the market. This
formulation has not been already deeply tested specific antiplaque studies in which the
structure of the biofilm remained intact.
The aim of this study was to evaluate the in situ antiplaque effect of 2 antimicrobial agents
(based on an essential oils formulation with and without alcohol) in the short term with a
posterior analysis on "non-destructured" biofilm with Confocal Laser Scanning Microscope
combined with fluorescence staining.