Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
INESS Antibiotic Prophylaxis in Orthopedic Guide recommends the use of Cefazolin at induction
for all orthopaedic procedure with implantation of internal fixation device. With the
increasing rate of identified P. acnes shoulder surgery infection despite the use of
recommended skin preparation and preoperative prophylactic antibiotics, a question arises; Is
Cefazolin the most effective prophylactic antibiotic for shoulder surgery? The objective of
this study is to determine if Ceftriaxone is superior to Cefazolin as a prophylactic
antibiotic for skin colonization with P. acnes in primary shoulder surgery