Antimicrobial Catheter Lock Solution for the Treatment of Central Line Associated Bloodstream Infection (CLABSI)
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
A CVC is a sterile flexible tube that allows a drug to flow from a bottle or bag directly
into a patient's bloodstream. CVCs may cause infections when bacteria gets into the catheter
and enters the bloodstream. They also have a risk of becoming clogged. When this occurs, the
CVC usually needs to be replaced.
The goal of this clinical research study is to learn if an antimicrobial catheter lock
solution can make it possible for the CVC to stay in place while treating an infection with
antibiotics. The safety of the solution will also be tested.
Your outcome will be compared to the outcome of patients who had the same type of infection
but had their CVC removed.
The antimicrobial catheter lock solution is made up of 3 chemicals:
Minocycline and ethanol are designed to disinfect the CVC. Disodium
ethylenediaminetetraacetate is designed to prevent the CVC from clogging.