Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
Status:
Completed
Trial end date:
2002-03-01
Target enrollment:
Participant gender:
Summary
To determine if the combined incidence of nonfatal myocardial infarction and coronary heart
disease death differs between diuretic-based and each of three alternative antihypertensive
pharmacological treatments. Also, to determine, in a subset of this population, if lowering
serum cholesterol with a HMG CoA reductase inhibitor in older adults reduces all-cause
mortality compared to a control group receiving usual care. Conducted in conjunction with the
Department of Veterans' Affairs.