Overview

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Status:
Completed
Trial end date:
2002-03-01
Target enrollment:
0
Participant gender:
All
Summary
To determine if the combined incidence of nonfatal myocardial infarction and coronary heart disease death differs between diuretic-based and each of three alternative antihypertensive pharmacological treatments. Also, to determine, in a subset of this population, if lowering serum cholesterol with a HMG CoA reductase inhibitor in older adults reduces all-cause mortality compared to a control group receiving usual care. Conducted in conjunction with the Department of Veterans' Affairs.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Amlodipine
Angiotensin-Converting Enzyme Inhibitors
Chlorthalidone
Doxazosin
Lisinopril
Pravastatin
Criteria
Men and women hypertensive patients, ages 55 and above. A total of 36 percent were
diabetics.