Antidepressants to Promote Recovery of Cardiac Patients Suffering From Depression
Status:
Terminated
Trial end date:
2011-04-01
Target enrollment:
Participant gender:
Summary
Depression is frequently seen in cardiac patients. It has been shown that depression often
has a negative impact on the course of coronary disease. More recently, research has
demonstrated that some antidepressants can be used safely to treat depressed coronary
patients. Although the majority of patients improve substantially with antidepressant
treatment, a significant proportion do not respond to antidepressants. This project seeks to
better understand why depression does not improve equally well in all patients. Ultimately,
the hope is to improve the treatments available to people affected by both cardiac disease
and depression, and to help select the best type of treatment in advance for each individual
based on his or her personal history, and biological characteristics.
Phase:
Phase 4
Details
Lead Sponsor:
Centre hospitalier de l'Université de Montréal (CHUM)
Collaborators:
Canadian Institutes of Health Research (CIHR) Centre de Recherche du Centre Hospitalier de l'Université de Montréal Montreal Heart Institute