Antidepressant Medication for Reducing HIV Risk Behavior in Depressed Intravenous Drug Users

• Status: Completed
• Trial end date: 2004-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate the effectiveness of antidepressant medication treatment in reducing HIV risk behaviors in intravenous drug users with depression.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Butler Hospital
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Antidepressive Agents

Criteria

Inclusion Criteria:

• DSM-IV diagnosis of major depression, dysthymia, substance-induced major depression, or major depression plus dysthymia

• Score of greater than 14 on the Hamilton Rating Scale for Depression

• Current opiate or cocaine use

• History of injection equipment sharing

• English-speaking

Exclusion Criteria:

• History of injection equipment sharing within 6 months of study entry

• Currently at risk for suicide

• Currently experiencing symptoms of psychosis

• Currently taking any other psychotropic medication

• Diagnosed with bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, or paranoid disorder

• Informed that treatment with antidepressant medications is medically inadvisable

• Pregnant