Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients
Status:
Completed
Trial end date:
2016-10-12
Target enrollment:
Participant gender:
Summary
The primary purpose of this protocol is to compare PDE4 levels before and after starting a
selective serotonin reuptake inhibitor (SSRI) sertraline, citalopram or escitalopram in
unmedicated depressed patients. The secondary purpose is to compare PDE4 levels between
unmedicated depressed patients and healthy subjects.