Anticoagulant Therapy During Pacemaker Implantation
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
There are no established guidelines regarding interruption of warfarin anticoagulant therapy
prior to surgical implantation of cardiac pacemakers. Continuing the anticoagulant could
potentially result in increased bleeding complications from the implantation surgery, whereas
discontinuing the anticoagulant could predispose the patient to blood clots and strokes. In
this study we intend to randomly assign warfarin-treated patients either into interrupted or
continued warfarin therapy prior to pacemaker implantation with the purpose of establishing
the rate of complication in these groups. Our hypothesis is that a cardiac pacing device can
be safely implanted without discontinuation of the anticoagulant therapy.
Phase:
Phase 4
Details
Lead Sponsor:
University of Turku
Collaborators:
Oulu University Hospital Satakunta Central Hospital Tampere University Hospital