Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine

• Status: Completed
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Anticholinergic drugs have traditionally been used for their antisialagogue properties. But use of anticholinergic drugs can interfere with thermoregulation via inhibition of the parasympathetically mediated sweat secretion. Sweating inhibition can reduce heat elimination, and children's thermoregulation depend more on sweating than adults and they can become hyperthermic when given these agents.

The investigators evaluated the fever-causing effects of adjunctive anticholinergics in children under general anesthesia using ketamine.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Inje University
• Treatments: Cholinergic Antagonists; Glycopyrrolate; Ketamine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) Physical Status classification I

• underwent surgery between 8 to 9 am

• undergoing ambulatory anesthesia with ketamine

Exclusion Criteria:

• who required endotracheal intubation

• who were administered with medications other than ketamine