Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission
Status:
Completed
Trial end date:
2004-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to see if antibiotic drugs given to treat an infection of the
uterus during pregnancy can reduce the chances of HIV being passed from an HIV-positive
mother to her baby.
A link between bacterial disease of the vagina, premature birth, infection of the uterus
during pregnancy, and the passing of HIV from a mother to her baby has been found. Early
treatment of these problems may reduce the risk of passing HIV from an HIV-positive mother to
her baby.
[Note: As of 02/21/03, enrollment into this study was halted because preliminary data showed
that the study antibiotics were not effective in preventing mother-to-child HIV
transmission.]
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators:
National Institute of Mental Health (NIMH) National Institute on Drug Abuse (NIDA)