The goal of this clinical trial is to examine immune responses to the BCG vaccine in healthy
adults who have, or who have not, taken antibiotics to deplete their gut bacteria prior to
vaccination.
The main question it aims to answer is: does depletion of the gut microbiota lead to impaired
BCG-induced protection against specific and non-specific to challenges to the immune system?
Phase:
Phase 4
Details
Lead Sponsor:
South Australian Health and Medical Research Institute
Collaborators:
Centenary Institute of Cancer Medicine and Cell Biology Flinders University Royal Adelaide Hospital Telethon Kids Institute University of Sydney