Antibiotic Treatment Alone for Acute Simple Appendicitis in Children
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
Appendectomy for acute appendicitis has recently been questioned as being the only correct
treatment for appendicitis. Appendectomy has been reported to have significant early and late
morbidity. This can be avoided with antibiotic treatment alone. Moreover, better quality of
life and lower costs have been associated with antibiotic treatment alone. Five clinical
trials in selected patients (males, older than 18 years) comparing appendectomy and
antibiotic treatment alone as primary mode of treatment found that antibiotic treatment alone
is safe and effective in 48-95% of the patients Conclusive evidence with regard to the
efficacy of antibiotic treatment alone in children with proven acute appendicitis however is
lacking. We propose a prospective cohort study to answer the following questions:
Phase:
N/A
Details
Lead Sponsor:
Ramon R. Gorter
Collaborators:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Flevoziekenhuis Red Cross Hospital Beverwijk St. Antonius Hospital