Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso
Status:
Completed
Trial end date:
2019-09-01
Target enrollment:
Participant gender:
Summary
The use of antibiotics has saved millions of human lives, however consumption of antibiotics
can select for antibiotic resistant organisms and may lead to changes in commensal
microbiome. This study is designed to estimate the effect of antibiotic consumption on
microbiome in a rural region of rural Burkina Faso. Changes in the intestinal and
nasopharyngeal microbiome and resistome following a short course of antibiotics will be
measured.
Phase:
Phase 4
Details
Lead Sponsor:
University of California, San Francisco
Collaborators:
Centre de Recherche en Sante de Nouna, Burkina Faso Heidelberg University
Treatments:
Amoxicillin Anti-Bacterial Agents Antibiotics, Antitubercular Azithromycin Trimethoprim, Sulfamethoxazole Drug Combination