Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Status:
Completed
Trial end date:
2011-11-01
Target enrollment:
Participant gender:
Summary
Aim of prospective randomized a placebo controlled study is to prove that in case of acute
surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel
and stomach appropriately administered antibiotic prophylaxis is effective with lower
incidence of infection in surgical site and comparable risk of development of other
nosocomial infections versus group without antibiotic prophylaxis. Secondary aim is to
determine risk of developing nosocomial infection in the above mentioned group of patients,
identify group of patients which does not benefit from prophylaxis, and compile financial
costs for antibiotic prophylaxis and treatment of nosocomial infections and thus the
background for the recommended procedure with regards that such prospective study does not
exist in the Czech Republic.