Antibiotic Prophylaxis for Neurogenic Bladder Botox
Status:
Not yet recruiting
Trial end date:
2023-08-31
Target enrollment:
Participant gender:
Summary
Injection of Botox into the bladder is a procedure used to treat neurogenic overactive
bladder at the Dianne and Irving Kipnes Urology Centre in the Kaye Edmonton Clinic. A common
complication following bladder Botox is bladder infection. There are no well-studied
preventative antibiotics given at the time of bladder Botox for the reduction of
post-operative bladder infection. We are proposing a research study that will randomize
participants into two groups - one receiving antibiotics and the other receiving placebo
pills following bladder Botox. The main goal of our study is to determine if preventative
antibiotics at the time of bladder Botox injection reduces post-operative bladder infection.
It will provide a valuable learning opportunity for a trainee starting their academic career
through working closely with established researchers across two disciplines. We hope the
results of our study can ultimately be used to improve outcomes and safety for a common
Urologic procedure. In addition, findings from our study could help reduce unnecessary use of
antibiotics resulting in cost savings in the health care system and reduction in the risk of
antibiotic resistance.