Injection of Botox into the bladder is a common treatment for overactive bladder.
Postoperative bladder infection is one of the more frequently reported complications of this
procedure. Prophylactic antibiotics given at the time of bladder Botox for the reduction of
postoperative bladder infection have not been well studied. The main goal of our study is to
determine if prophylactic antibiotics at the time of bladder Botox injection for the
treatment of overactive bladder in women reduces postoperative bladder infection. The
investigators are proposing a study which will randomize participants into two groups - one
receiving Ciprofloxacin and the other receiving placebo pills for three days following the
procedure. The primary outcome evaluated will be the difference in postoperative bladder
infection between the two groups. The investigators will also investigate differences in
reported side effects between the two groups possibly related to antibiotic use. Follow-up
will be over six weeks following the procedure.
Phase:
Phase 4
Details
Lead Sponsor:
University of Alberta
Collaborator:
Women and Children's Health Research Institute, Canada