Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique

• Status: Completed
• Trial end date: 2018-12-28

Summary

• The teeth of the patients that meet inclusion criteria will be anesthetized, isolated with a rubber dam.

• Cavity opened using conventional high-speed rotary instruments.

• The central cariogenic biomass and the superficial parts of the necrotic dentine will be removed with round burs.

• Caries lesion will be completely removed in the enamel/dentin junction.

• The excavation procedure will be terminated as soon as the soft and wet dentine was removed and the remaining tissue was leathery but not hard on exploring.

• A dentinal sample will then be collected from the base of the cavity using sterile spoon excavator as a baseline for bacteriological assessment.

• Then, application of either intervention or control agent, another dentinal sample will be collected using a sterile excavator and transferred into sterile tubes and transferred to the laboratory for microbiological analysis.

• Filling of the cavity with resin composite restoration.

• All clinical procedures will be carried out at the same visit.

• Phase: Phase 3

Details

• Lead Sponsor: Cairo University
• Treatments: Anti-Bacterial Agents; Chlorhexidine; Chlorhexidine gluconate; Fluorides; Pharmaceutical Solutions