AntiPlatelet theraPy stratEgy followiNg Left Atrial appenDAGe closurE
Status:
Not yet recruiting
Trial end date:
2022-11-15
Target enrollment:
Participant gender:
Summary
The APPENDAGE study is a phase 4 multicentre randomized opened clinical trial comparing 2
different antithrombotic strategies following left atrial appendage closure (LAAC) in
patients with non valvular atrial fibrillation (AF). The primary objective of the study is to
evaluate the efficacy of Aspirin versus Aspirin + Clopidogrel after LAAC by comparing the
occurrence of ischemic lesions on cerebrovascular magnetic resonance imaging (MRI) studies.