Overview

AntiCoagulants and COGnition

Status:
Not yet recruiting
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the change of global cognitive performance after 52 weeks of intervention among participants with nonvalvular atrial fibrillation (NVAF) receiving rivaroxaban versus a vitamin K antagonist (warfarin). The secondary objectives are to compare, among participants with NVFA receiving rivaroxaban versus warfarin : - the changes of global cognitive performance after 26 weeks of intervention - the changes of executive functions after 26 and 52 weeks of intervention - the changes of episodic memory after 26 and 52 weeks of intervention - the volumetric changes of the brain after 26 and 52 weeks of intervention - the changes of independence and autonomy after 26 and 52 weeks of intervention - the changes of serum vitamin K concentration after 26 and 52 weeks of intervention
Phase:
Phase 4
Details
Lead Sponsor:
University Hospital, Angers
Collaborator:
Bayer
Treatments:
Anticoagulants
Rivaroxaban
Warfarin