Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosis

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to determine whether 6 months of anti-HIV drugs given along with tuberculosis treatment will delay the onset of AIDS in HIV infected African patients.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
• Collaborator: Makerere University
• Treatments: Abacavir; Lamivudine; Zidovudine

Criteria

Inclusion Criteria:

• Diagnosis of pulmonary TB (AFB smear-positive or culture-positive)

• HIV infected

• CD4 count greater than 350 cells/mm3

• Residence within 20 km of Kampala, Uganda

• Willing to use acceptable forms of contraception during the study and for 6 weeks after stopping study medication

• Parent or guardian willing to provide informed consent, if applicable

Exclusion Criteria:

• Pregnancy