Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy

• Status: Completed
• Trial end date: 2013-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Opioids may attenuate postoperative hyperalgesia and postoperative nausea and vomiting. Our hypothesis is: opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy may achieve comparable hemodynamic stability during laparoscopy, with lower postoperative analgesic consumption and incidence of postoperative nausea and vomiting.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bezmialem Vakif University
• Treatments: Analgesics, Opioid; Anesthetics; Dexmedetomidine; Lidocaine; Propofol; Remifentanil

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists I-II patients

• 20-60 years

Exclusion Criteria:

• American Society of Anesthesiologists III and above patients

• BMI: 35 and above

• Hepatic, renal or cardiac insufficiency

• 2 degree Heart block and above

• Diabetes

• Psychiatric disease

• History of chronic pain

• Alcohol or drug abuse

• Allergy to any of a drug in the study groups

• Pregnant, breast-feeding or menstruating women

• Inability to use a patient-controlled analgesia device

• Any analgesic or antiemetic use in last 24 hours before anesthesia induction

• Any surgical complication that may affect the outcomes of the study (open surgery etc.)