Anesthesia Depth's Influence on Postoperative Delirium
Status:
Unknown status
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The investigators,according to the eligibility criteria,plane to choose 80 elderly
anticipates who will undergo selective hip replacement surgery.This participants will be
randomly divided into 2 groups:light anesthesia depth group(L Group) and deep anesthesia
depth group (D Group).Before anesthesia induction,each participant will be given lumbar
plexus and sciatic nerve block in order to control pain of interoperative and
postoperative.During operation period,the L Group will be kept in light anesthesia
depth(BIS:50-60),while the D group will be kept in deep anesthesia depth(BIS:35-45)--The BIS
values in the range of 30-60 have been recommended in general anesthesia.After operation,a
PCIA(patient controlled intravenous analgesia) analgesia pump will be given to each
participant to control postoperative pain. The investigator will evaluate the mental state of
participant with MMSE(mini-mental state examination) before surgery and review each
participant with a CAM-CR for 3 days after surgery to assess the situation of postoperation
delirium.intraoperative awareness,postoperative pain will also be investigated in
postoperative days 1, 2, 3.