Androcur Non-interventional Study Among Patients With Carcinoma of the Prostate
Status:
Terminated
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
Cyproterone acetate (CPA) is a steroidal antiandrogen which has affinity with progesterone
and with glucocorticoid receptors. Cyproterone acetate is long-term proven effective
treatment of inoperable carcinoma of the prostate.
Sexual functions remain very important in men with prostate cancer. However sexual functions
are deteriorating fast with course of the disease. The influence of CPA on sexual functions
remains controversial. IIEF-5 erectile dysfunction questionnaire is currently widely used
validated simple scoring system for diagnosing of erectile dysfunction and belongs to most
used systems in Czech Republic. At present there are no data on CPA influence on IIEF-5
scored erectile dysfunction within the use of its indication in prostate cancer.