Overview

AndroGel in Men With Major Depression and Incomplete Response to Antidepressant Treatment

Status:
Completed
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
We hypothesize that AndroGel may offer some relief to subjects with low or borderline testosterone levels who suffer from depression and have failed to respond to a trial of a standard antidepressant. During this nine week, outpatient, double-blind study, male subjects between the ages of 30 and 65 years with treatment-refractory depression and low or borderline low testosterone levels will be treated with either AndroGel or placebo. Following this nine week, double-blind phase, eligible subjects will have the option to continue into a six month, open-label phase during which time all subjects will receive the AndroGel patch.
Phase:
Phase 4
Details
Lead Sponsor:
Mclean Hospital
Collaborator:
Solvay Pharmaceuticals
Treatments:
Antidepressive Agents
Methyltestosterone
Testosterone
Testosterone 17 beta-cypionate
Testosterone enanthate
Testosterone undecanoate