The skin and gut microbiome of rosacea patients differs from individuals without rosacea and
that the microbiome suffers from unique derangements in rosacea patients following antibiotic
therapy.
This study was proposed to examine microbial signatures of the skin and gut microbiome in
patients with moderate to severe rosacea and to identify differences between microbe
communities in patients with rosacea and volunteers without rosacea using 16S ribosomal
ribonucleic acid (rRNA) polymerase chain reaction (PCR) amplification, sequencing and
computational phylogenetics and to assess alterations in the gut and skin microbiota of
patients with moderate to severe rosacea in response to varying formulations of antimicrobial
treatment.