Analysis of the Effect of Iron Supplements on Iron Deficiency Anemia in Pregnancy
Status:
Recruiting
Trial end date:
2025-01-01
Target enrollment:
Participant gender:
Summary
Subjects were tested for hemoglobin, ferritin, serum iron, transferrin saturation and
reticulocyte count during routine prenatal examination at 24-26 weeks of gestation, and blood
samples were taken for serum hepcidin detection in the laboratory and the values were
recorded. Those who met the criteria were included in the study group, signed the informed
consent form and randomized into groups, and were given different drug administration schemes
(150mg orally every day, 300mg orally every day, 150mg orally every other day, 300mg orally
every other day, intravenous). At the same time, each subject was given anemia diet
education, and all subjects were given folic acid 400ug/d and vitamin C 0.5g/d orally during
the treatment period. If the subjects were in the oral iron group, the same time of oral iron
was determined as 20 o'clock ± 1 hour in the evening, and the oral iron was not taken with
other drugs; If the subject is in the intravenous medication group, the medication is
scheduled to be administered at a uniform time of 8 o'clock ± 1 hour in the morning. The
above subjects were followed up. Hemoglobin, ferritin, serum iron, transferrin saturation and
reticulocyte count were performed at 30-32 and 37 weeks of pregnancy and delivery, and blood
samples were taken for serum hepcidin detection in the laboratory and the values were
recorded. The adverse reactions were investigated with a questionnaire at the last prenatal
examination before delivery. After full term delivery, the patient fills in the delivery
information and enters it into the database. Finally, the data statistician and the above
personnel used the blind method for statistical analysis and reached a conclusion.