Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection
Status:
Completed
Trial end date:
2018-06-13
Target enrollment:
Participant gender:
Summary
This research project will study whether the drug telmisartan administered in conjunction
with antiretroviral therapy (ART) will help reduce nervous system infection with HIV. The
investigators are studying the effect of this treatment in people who have contracted HIV
infection within the past three weeks, and thus have a form of HIV called acute HIV
infection. The investigators will measure biological markers of immune activation in the
blood and cerebrospinal fluid to see if telmisartan may reduce the spread of HIV reservoirs
in affected patients.
Phase:
Phase 1
Details
Lead Sponsor:
Yale University
Collaborators:
National Institute of Mental Health (NIMH) National Institute of Neurological Disorders and Stroke (NINDS) South East Asia Research Collaboration with Hawaii University of California, San Francisco University of Hawaii Walter Reed Army Institute of Research (WRAIR)