Overview

Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Fentanyl

Status:
Completed
Trial end date:
2020-11-18
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this project is to test how fentanyl, an analgesic currently employed in the pre-hospital setting by the US Army, alters the capacity to tolerate a hemorrhagic insult in humans.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborator:
United States Department of Defense
Treatments:
Analgesics
Fentanyl
Criteria
Inclusion Criteria:

- Healthy

- Non-obese (body mass index less than 30 kg/m2)

- Body mass greater than or equal to 65 kg

Exclusion Criteria:

- Subjects who have cardiac, respiratory, neurological and/or metabolic illnesses

- Any known history of renal or hepatic insufficiency/disease

- Pregnancy or breast feeding

- Current smokers, as well as individuals who regularly smoked within the past 3 years

- Positive urine drug screen

- Currently taking pain modifying medication(s)