Analgesic Potentials of Preoperative Pregabalin,Magnesium Sulphate and Their Combination in Acute Post-thoracotomy Pain
Status:
Completed
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
This study evaluates the effect of giving preoperative adjuvant drug as pregabalin or
magnesium sulphate or a combination of both drugs to decrease postoperative morphine
consumption and pain intensity in the first 24 hours in postoperative period . quarter of
patients receive single dose oral pregabalin 300mg 1 hour preoperatively ,other quarter
receive single intravenous Magnesium sulphate 50mg per Kg over 200ml saline over 20 minutes
preoperatively , other quarter receive combination of both drugs , the last quarter receive
placebo drugs . All patients receive 0.1mg per Kg intravenous morphine sulphate
intraoperatively