Overview

Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.

Status:
Recruiting
Trial end date:
2022-08-31
Target enrollment:
0
Participant gender:
All
Summary
The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, compared to ropivacaine alone in patients undergoing Video-Assisted thoracoscopic Surgery (VATS) procedures.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Aga Khan University
Treatments:
Analgesics
BB 1101
Dexamethasone
Dexamethasone acetate
Dexmedetomidine
Ketamine
Midazolam
Ropivacaine
Tramadol
Criteria
Inclusion Criteria:

1. ASA I to III.

2. Age >18 years.

3. Either sex.

4. Elective Video assisted thoracotomy surgery (VATS) under general anaesthesia

Exclusion Criteria:

1. ASA IV & V.

2. Coagulation disorders.

3. Infection at the vicinity of the surgical wound.

4. Raised intracranial pressure.

5. History of hypersensitivity or known allergy to any study drug.

6. History of opioid addiction.

7. History of seizure disorder.

8. Those who are not willing to participate in the study.

9. Allergy to local anesthetics.

10. Duration of surgery greater than 2 hours.