Analgesic Efficacy of Intranasal Desmopressin in Acute Renal Colic

• Status: Unknown status
• Trial end date: 2013-03-01
• Target enrollment: 0
• Participant gender: All

Summary

In this study we will compare pain intensity and side effects at different time points after the intranasal administration of desmopressin or placebo in patients with acute renal colic pain.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tehran University of Medical Sciences
• Treatments: Analgesics; Deamino Arginine Vasopressin; Indomethacin

Criteria

Inclusion Criteria:

• Age: 15 to 65 years

• Pain intensity of at least 3

• Clinical diagnosis of renal colic

Exclusion Criteria:

• History of hypertension

• History of acute myocardial ischemia

• History of hyponatremia

• Presence of acute rhinitis and flu

• Coagulopathy or anticoagulant therapy

• History of peptic ulcer disease, asthma, renal failure, severe liver failure

• Analgesic use over 4 hours ago

• Taking seizure medications (such as carbamazepine)

• Taking any of the following drugs: chlorpropamide, warfarin, clofibrate , epinephrine, Fludrocortisone, heparin, lithium, alcohol