Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias
Status:
Recruiting
Trial end date:
2025-05-01
Target enrollment:
Participant gender:
Summary
Caudal analgesia with ropivacaine is commonly used in sub-umbilical pediatric surgery.
However, increasing the dosage of ropivacaine has not been found to prolong the action
significantly while complications will be serious.
Ketamine as an additive to caudal administration had been shown to prolong the duration of
postoperative analgesia, while the analgesic effectiveness of S-ketamine, the S(+)-enantiomer
of ketamine with less possibility to induce psychomotor disturbances, is not clear. In this
prospective randomized double-blind clinical trial , the investigators aimed to study the
effect of S-ketamine as additive on the duration of caudal analgesia.